Biochemical and Molecular Characterization of Three New Variants of AmpC -Lactamases from Morganella morganii
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چکیده
Biochemical and Molecular Characterization of Three New Variants of AmpC -Lactamases from Morganella morganii Pablo Power, Moreno Galleni, Juan A. Ayala, and Gabriel Gutkind* Cátedra de Microbiologı́a, Facultad de Farmacia y Bioquı́mica, Universidad de Buenos Aires, Junı́n 954, Buenos Aires 1113, Argentina; Centre d’Ingénierie des Protéines, Université de Liège, Institut de Chimie, B6 (B4000), Sart Tilman, Belgium; and Centro de Biologı́a Molecular “Severo Ochoa,” CSIC-UAM, Campus de Cantoblanco 28049, Madrid, Spain
منابع مشابه
Biochemical and molecular characterization of three new variants of AmpC beta-lactamases from Morganella morganii.
Morganella morganii produces an inducible, chromosomally encoded AmpC beta-lactamase. We describe in this study three new variants of AmpC within this species with apparent pIs of 6.6 (M19 from M. morganii strain PP19), 7.4 (M29 from M. morganii strain PP29), and 7.8 (M37 from M. morganii strain PP37). After gene sequencing, deduced amino acid sequences displayed one to six substitutions when c...
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